Hereditary Spherocytosis in a Malay Patient with Chronic Heamolysis

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Published: Jul 31, 2007
DOI: https://doi.org/10.21315/
Keywords:
Hereditary spherocytosis, Jaundice, Chronic haemolysis, Leucoerythroblastic picture. Microspherocytes.

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Muhammad Kamil Sheikh
Advanced Medical and Dental Institute (Clinical Centre, Universiti Sains Malaysia No. 29 Lorong Bertam Indah 4/9, Taman Bertam Indah, 13200 Kepala Batas, Penang Malaysia.
Narazah Mohd. Yusoff
Advanced Medical and Dental Institute (Clinical Centre, Universiti Sains Malaysia No. 29 Lorong Bertam Indah 4/9, Taman Bertam Indah, 13200 Kepala Batas, Penang Malaysia.
Gurjeet Kaur
Advanced Medical and Dental Institute (Clinical Centre, Universiti Sains Malaysia No. 29 Lorong Bertam Indah 4/9, Taman Bertam Indah, 13200 Kepala Batas, Penang Malaysia
Farhat Aziz Khan
Advanced Medical and Dental Institute (Clinical Centre, Universiti Sains Malaysia No. 29 Lorong Bertam Indah 4/9, Taman Bertam Indah, 13200 Kepala Batas, Penang Malaysia.

Abstract

This case report describes a 35-year-old lady who presented with generalized weakness and lethargy of two weeks duration and jaundice of more than 20 years duration. Her initial workup was suggestive of haemolysis and blood film showed a leucoerythoblastic picture with moderate microspherocytes. She was finally diagnosed as a case of hereditary spherocytosis after ruling out other possible causes of chronic haemolysis and supported by an abnormal osmotic fragility test, although family members refused for screening. Hereditory spherocytosis is uncommon in Malay population and presentation with jaundice of 20 years duration with leucoerythroblastic picture on blood film were interesting features in this case. Patient is being followed closely for need of splenectomy in near future as per severity of haemolysis and currently being managed with folic acid supplement.

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How to Cite
1.
Muhammad Kamil Sheikh, Narazah Mohd. Yusoff, Gurjeet Kaur, Farhat Aziz Khan. Hereditary Spherocytosis in a Malay Patient with Chronic Heamolysis. Malays J Med Sci [Internet]. 2007 Jul. 31 [cited 2026 Oct. 22];14(2):54-7. Available from: https://ejournal.usm.my/mjms/article/view/mjms_vol14-no2-2007-9
Issue
Vol. 14 No. 2 (2007)
Section
Original Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

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