Paediatric myelodysplastic syndrome: A case report

Abstract

A 11 year old boy presented with a 2 month history of fever, lethargy and bruising. Pallor petechiae and ecchymoses were found on examination. The blood count showed pancytopenia and bone marrow examination was consistent with myelodysplastic syndrome, refractory anaemia subtype under the FAB classification. He required regular blood product support over the next 15 months but he eventually died of intracerebral haemorrhage without evidence of progression to frank leukaemia. Current knowledge of the paediatric myelodysplastic syndromes is briefly reviewed.