General Paresis of Insane: A diagnostic dilemma

Abstract

Two atypical cases of General Paresis of Insane (G.P.I) with diagnostic difficulty is reported. They presented mainly as behavioural problems prior to the development of any physical sign. The physical signs were also few and not diagnostic per se of G.P.I. The diagnostic problem was further compounded by the lack of consent for lumber puncture which is common in this part of the country due to the prevailing cultural belief system. The diagnostic and therapeutic implications are discussed.