Neuroanatomy and Neurophysiology of the Corrupt-Prone Brain: Where Morality, Cognition, and Behaviour Intersect
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Abstract
In Malaysia, corruption analyses and brain, and mind and neuroscience; are two critical domains of enquiry that seek to advance research that bridges medicine, clinical neurophysiology and neurotechnology by 2050. Local universities, both public and private, must initiate studies into how corruption and malpractice—and their resulting economic losses to the nation—can be prevented. An understanding of neuroanatomy, neurophysiology. and neurochemistry will hopefully advance knowledge of how the human brain can be trained to resist corruption and, eventually, be rehabilitated
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References
Graycar A, Smith RG. Handbook of global research and practice corruption. Cheltenham: Edward Elgar; 2013.
Diamond A. Normal development of prefrontal cortex from birth to young adulthood: cognitive functions, anatomy, and biochemistry. In: Principles of Frontal Lobe Function. Oxford University Press; 2002. p. 466–503. https://doi.org/10.1093/acprof:oso/9780195134971.003.0029
Kolk SM, Rakic P. Development of prefrontal cortex. Neuropsychopharmacology. 2022;47:41–57. https://doi.org/10.1038/s41386-021-01137-9
Zhu L, Jenkins AC, Set E, Scabini D, Knight RT, Chiu PH, et al. Damage to dorsolateral prefrontal cortex affects tradeoffs between honesty and self-interest. Nat Neurosci. 2014;17:1319–1321. https://doi.org/10.1038/nn.3798
Zhang D, Zhang S, Lei Z, Li Y, Li X, Gu R. Why people engage in corrupt collaboration: an observation at the multi-brain level. Cereb Cortex. 2023;33(13):8465–8476. https://doi.org/10.1093/cercor/bhad132
Liu J, Gu R, Liao C, Lu J, Fang Y, Xu P, et al. The neural mechanism of the social framing effect: evidence from fMRI and tDCS studies. J Neurosci. 2020;40(18):3646–3656. https://doi.org/10.1523/JNEUROSCI.1385-19.2020
Hu Y, Philippe R, Guigon V, Zhao S, Derrington E, Corgnet B, et al. Perturbation of right dorsolateral prefrontal cortex makes power holders less resistant to tempting bribes. Psychol Sci. 2022;33(3):412–423. https://doi.org/10.1177/09567976211042379
Fan B, Mao W, Jin J, Ma Q. Modulating activity in the dorsolateral prefrontal cortex alter corruption behavior: a transcranial direct current stimulation study. Behav Brain Res. 2020;382:112479. https://doi.org/10.1016/j.bbr.2020.112479
Jung J, Lambon Ralph MA, Jackson RL. Subregions of DLPFC display graded yet distinct structural and functional connectivity. J Neurosci. 2022;42(15):3241–3252. https://doi.org/10.1523/JNEUROSCI.1216-21.2022
Bruno A, Lothmann K, Bludau S, Mohlberg H, Amunts K. New organizational principles and 3D cytoarchitectonic maps of the dorsolateral prefrontal cortex in the human brain. Front Neuroimaging. 2024;3:1339244. https://doi.org/10.3389/fnimg.2024.1339244
Sánchez-Fernández J, Casado-Aranda LA. Neural predictors of changes in party closeness after exposure to corruption messages: an fMRI study. Brain Sci. 2021;11(2):158. https://doi.org/10.3390/brainsci11020158
Yoon JH, Grandelis A, Maddock RJ. Dorsolateral prefrontal cortex GABA concentration in humans predicts working memory load processing capacity. J Neurosci. 2016;36(46):11788–11794. https://doi.org/10.1523/JNEUROSCI.1970-16.2016
Yu Q, Abe N, King A, Yoon C, Liberzon I, Kitayama S. Cultural variation in the gray matter volume of the prefrontal cortex is moderated by the dopamine D4 receptor gene (DRD4). Cereb Cortex. 2019;29(9):3922–3931. https://doi.org/10.1093/cercor/bhy271
Danilova AA. Neurobiological markers corruption behavior: theoretical review. Vestn Chelyab Gos Univ Obraz Zdravookhr. 2024;25(1):41–49. https://doi.org/10.47475/2409-4102-2024-25-1-41-49
Hu Y, Hu C, Derrington E, Corgnet B, Qu C, Dreher JC. Neural basis of corruption in power-holders. eLife. 2021;10:e63922. https://doi.org/10.7554/eLife.63922
Ponce-Díaz CR, Aiquipa-Tello JJ, Pacheco-Luza EF, Pezúa-Vasquez RL. Tests assessing corrupt behavior from a psychological perspective. Eur J Psychol Assess. 2026;42(1):34–47. https://doi.org/10.1027/1015-5759/a000833
Vilanova F, Milfont TL, Costa AB. A dual process social psychological model of corrupt intention and attitudes toward corrupt people. J Pers Soc Psychol. 2022;123(4):854–883. https://doi.org/10.1037/pspp0000414
Manara MU, Nübold A, van Gils S, Zijlstra FRH. Exploring the path to corruption–an informed grounded theory study on the decision-making process underlying corruption. PLoS One. 2023;18(9):e0291819. https://doi.org/10.1371/journal.pone.0291819
Galan S. Latin America: bribery victimization rate 2004-2023 [Internet]. New York (NY): Statista; 2025 Nov 28. Available at: https://www.statista.com/statistics/1067028/bribery-victimization-rate-latin-america/
Carlos LG de C, Kochi TG, Cintra RF, Ribeiro I. Corruption in public service: factors related to moral disengagement and organizational ethical culture. Rev Adm Publica. 2025;59(6): e2024–0496. https://doi.org/10.1590/0034-761220240496x
Greene JD, Nystrom LE, Engell AD, Darley JM, Cohen JD. The neural bases of cognitive conflict and control in moral judgment. Neuron. 2004;44(2):389–400. https://doi.org/10.1016/j.neuron.2004.09.027
Sobhani M, Bechara A. A somatic marker perspective of immoral and corrupt behavior. Soc Neurosci. 2011;6(5–6):640–652. https://doi.org/10.1080/17470919.2011.605592
Bîzoi AC, Bîzoi CG. Framing institutional corruption: a behavioral simulation of moral judgment and accountability narratives. SAGE Open. 2026;16(1):1–20. https://doi.org/10.1177/21582440261417024
Pozsgai-Alvarez J. Corruption tolerance as a process of moral, social, and political cognition: evidence from Latin America. Crime Law Soc Change. 2022;77:381–404. https://doi.org/10.1007/s10611-021-09995-6
Varraich A, Köbis NC, Lange J. The social psychology of corruption. Eur J Soc Psychol. 2025;55(3):419–423. https://doi.org/10.1002/ejsp.3165
Wijayanto W, Berenschot W, Suwana F. KPK and Taliban: cyber troops and the social media influence operation to weaken Indonesia’s anti-corruption body. Indonesia. 2025;119(1):103–121. https://doi.org/10.1353/ind.2025.a961929
Higson-Bliss L. Social Media, Criminal Law and Legality. London: Routledge; 2024. https://doi.org/10.4324/9781003303688
Odilla F, Veloso C. Citizens and their bots that sniff corruption: using digital technology to monitor and expose politicians who misuse public money. Am Behav Sci. 2026;70(8):1094–1116. https://doi.org/10.1177/00027642241268572
Wijayanto, Berenschot W, Sastramidjaja Y, Ruijgrok K. The infrastructure of domestic influence operations: cyber troops and public opinion manipulation through social media in Indonesia. Int J Press Polit. 2026;31(3):551–569. https://doi.org/10.1177/19401612241297832
Alcántara-Lizárraga JÁ, Jima-González A. Digital manipulation and mass mobilization over the long run: evidence from Latin America. Front Political Sci. 2024;6:1296004. https://doi.org/10.3389/fpos.2024.1296004
Alganami FH, El Keshky MESA. Corruption as an ethical issue; the Dark Triad, corrupt intention and the. J King Abdulaziz Univ Arts Humanit. 2022;30(4):353–365. https://doi.org/10.4197/Art.30-4.16
Incio J, Seifert M. How the perception of corruption shapes the willingness to bribe: evidence from an online experiment. Int J Public Opin Res. 2024;36(3):edae035. https://doi.org/10.1093/ijpor/edae035
Wei C, Dang J, Liu L, Li C, Tan X, Gu Z. Economic inequality breeds corrupt behaviour. Br J Soc Psychol. 2023;62(2):949–971. https://doi.org/10.1111/bjso.12610
Hortal A, Pérez Martínez A. Behavioral strategies for reducing corruption: from regulation to choice architecture. Behav Public Policy. 2026;10(3):597–614. https://doi.org/10.1017/bpp.2024.48
Wahyono H, Narmaditya BS. Structural model of the application of anti-corruption values to local government bureaucrats. Soc Sci Humanit Open. 2022;6(1):100346. https://doi.org/10.1016/j.ssaho.2022.100346