PRELIMINARY SCREENING OF ENDOPHYTIC FUNGI FROM MEDICINAL PLANTS IN MALAYSIA FOR ANTIMICROBIAL AND ANTITUMOR ACTIVITY

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Son Radu
Cheah Yoke Kqueen

Abstract

The screening of antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, yeast and fungi was carried out on isopropanol extracts prepared from 121 isolates of endophytic fungi isolated from medicinal plants in Malaysia. Sensitivity was found to vary among the microorganisms. Bacillus subtilis, Saccharomyces cerevisiae and Alternaria sp. were susceptible to extracts from three, two and two isolates of endophytic fungi, respectively. None were found effective against Salmonella typhimurium. Sixteen endophytic fungal isolates tested were also found to exhibit antitumor activity in the yeast cell-based assay.

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1.
Son Radu, Cheah Yoke Kqueen. PRELIMINARY SCREENING OF ENDOPHYTIC FUNGI FROM MEDICINAL PLANTS IN MALAYSIA FOR ANTIMICROBIAL AND ANTITUMOR ACTIVITY. Malays J Med Sci [Internet]. 2002 Jul. 31 [cited 2026 Oct. 18];9(2):23-3. Available from: https://ejournal.usm.my/mjms/article/view/mjms_vol9-no2-2002_4
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Original Articles